Glimizor-2 PM Tablets

Description

Glimizor-2 PM Tablets: Advanced Triple Therapy for Comprehensive Type 2 Diabetes Management

Glimizor-2 PM Tablets are a potent, triple-combination oral anti-diabetic medication designed to provide comprehensive blood sugar control in adults with Type 2 Diabetes Mellitus. This advanced formulation is typically prescribed when diet, exercise, and dual-therapy medications have not achieved sufficient glycemic control. By combining three distinct classes of anti-diabetic agents, Glimizor-2 PM targets multiple pathways involved in blood glucose regulation.

Key Ingredients and Their Synergistic Actions:

• Glimepiride (2mg): As a sulfonylurea, Glimepiride works primarily by stimulating the beta cells in the pancreas to increase the release of insulin. Insulin is essential for transporting glucose from the bloodstream into the body’s cells for energy, thereby effectively lowering blood glucose levels.
• Metformin (often Extended Release): A biguanide that acts on multiple fronts. It reduces the liver’s production of glucose (hepatic gluconeogenesis), delays glucose absorption from the intestines, and significantly improves the sensitivity of peripheral tissues (muscles and fat) to insulin. The “PM” in the name, combined with common formulations, often implies an extended-release form of Metformin, providing sustained action.
• Pioglitazone: A thiazolidinedione (TZD) that enhances insulin sensitivity in key target tissues, including muscle, adipose tissue, and the liver. It achieves this by activating specific receptors (PPAR-gamma) that regulate genes involved in glucose and lipid metabolism, allowing the body’s cells to utilize glucose more efficiently.

The combined effect of these three medications in Glimizor-2 PM provides a powerful approach to managing both fasting and post-meal blood sugar levels, helping to prevent the progression and complications of Type 2 Diabetes.

Key Benefits of Glimizor-2 PM Tablets:

• Multifaceted Blood Sugar Control: Addresses various aspects of glucose dysregulation, including insulin resistance, insufficient insulin production, and excessive liver glucose output.
• Reduced Risk of Complications: By effectively lowering and maintaining blood sugar within a target range, it helps significantly reduce the risk of long-term diabetes complications such as neuropathy (nerve damage), retinopathy (eye damage), nephropathy (kidney damage), and cardiovascular diseases (heart attack, stroke).
• Improved Insulin Sensitivity: Pioglitazone and Metformin work together to make the body’s own insulin more effective.
• Convenient Dosing: As a combination tablet, it simplifies the medication regimen compared to taking individual drugs.

Important Information and Precautions:

• Prescription Medicine: Glimizor-2 PM Tablets are a prescription-only medication. It is crucial to take them strictly as directed by your doctor. Do not alter the dose or discontinue the medication without medical consultation.
• Lifestyle Integration: This medication is an adjunct to a healthy lifestyle including a balanced diet, regular physical activity, and weight management as advised by your doctor.
• Risk of Hypoglycemia (Low Blood Sugar): Glimepiride can cause low blood sugar. Be aware of symptoms (sweating, dizziness, shaking, headache, confusion) and carry a rapid source of glucose (e.g., glucose tablets, fruit juice, sugar candies).
• Lactic Acidosis (Rare but Serious with Metformin): Metformin carries a rare but serious risk of lactic acidosis. Seek immediate medical attention if you experience unusual muscle pain, breathing difficulties, stomach pain, vomiting, or weakness. Avoid excessive alcohol consumption.
• Fluid Retention & Heart Failure (with Pioglitazone): Pioglitazone can cause fluid retention and may worsen or lead to heart failure in some patients. Inform your doctor about any history of heart failure or unusual swelling.
• Bladder Cancer Risk (with Pioglitazone): Pioglitazone has been associated with a small increased risk of bladder cancer. Report any blood in urine or pain during urination to your doctor.
• Bone Fractures (with Pioglitazone): Increased risk of bone fractures, especially in women.
• Liver Function: Regular monitoring of liver function tests is important, especially with Pioglitazone.
• Kidney Function: Metformin requires careful monitoring of kidney function.
• Vitamin B12 Deficiency: Long-term Metformin use can lead to Vitamin B12 deficiency.
• Pregnancy and Breastfeeding: Generally not recommended during pregnancy or breastfeeding. Discuss with your doctor.
• Side Effects: Common side effects include nausea, diarrhea, stomach pain, headache, and metallic taste.
• Storage: Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Composition: Glimepiride (2mg), Metformin Hydrochloride (often Extended Release), and Pioglitazone (strength usually 15mg or 7.5mg). Please refer to your specific product packaging for exact strengths and a complete list of ingredients.

Disclaimer: This information is for general knowledge and informational purposes only, and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before taking any medication.